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This is a precautionary concern

A class of peptic ulcer and antacid drugs called histamine H2 receptor agonists, including Tagamet, Zantac, and Pepcid Anticonvulsants including phenobarbital, primidone, and phenytoin Bile acid sequestrants including colestipol and cholestyramine, which lower cholesterol Chemotherapy medications like methotrexate Metformin, which is a diabetes drug Proton pump inhibitor drugs used to treat acid reflux, such as omeprazole (Prilosec), esomeprazole (Nexium), or lansoprazole (Prevacid) Tetracycline, an antibiotic Lastly, it is also essential that you communicate with your provider if you have kidney disease or an allergy to cobalt or any other medication, vitamin, dye, food, or preservative

Aesthetic Surgery Journal

Primary target: It binds to amylin and calcitonin receptors, helping regulate food intake and satiety at the brain level while also influencing digestion