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The lipoate moiety docked within the catalytic pocket, proximal to the catalytic serine-141 and histidine-296 residues (Fig

Vitamin E acts as a regulator of cellular metabolism, and its deficiency leads to anaemia, dysregulation of energy metabolism, irregular mitochondrial function, and tissue damage resulting from increased lipid peroxidation (170)

these changes have been closely associated with PPI-associated digestive complications (Malfertheiner et al., 2017), including functional dyspepsia (FD), SIBO, and C

We have therefore necessarily made a number of assumptions about the loss of GSH, GSSG, Cys, Gly, and Glu to other tissues