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PRDX1 stabilizes NFE2L2 by inhibiting cullin 3 (CUL3)-mediated ubiquitination, thereby promoting transcription of genes involved in GSH synthesis ( GCLC , GCLM ) and cystine import ( SLC7A11 ) 113

We propose an important contribution of de novo ser/gly synthesis pathway activation to RT responses by supplying ATP, nucleotides, and antioxidants to support the survival and/or recovery of cancer cells upon RT

A major determinant of bone length is the rate of differentiation of proliferating chondrocytes into hypertrophic chondrocytes