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Rights and permissions About this article Cite this article Madhu, Sharma, A., Kaur, A

Depletion-repletion studies, which are traditionally used for deriving dietary recommendations are inappropriate in pregnancy for health safety and ethical issues, thus other types of studies and indirect approaches need to be utilised

The formation of gamma-glutamylcysteine is the rate-limiting reaction in GSH synthesis and is feedback inhibited by GSH itself, a mechanism responsible for the regulation of cellular GSH concentration