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In the normal control group, histopathological alterations were observed, indicating potential baseline vulnerability in neuronal regions

To gain more insight into the effect of GSH paucity on mitochondria, we used MitoTracker (MT) green and MT red staining to assess mitochondrial membrane potential ( m ) with flow cytometry

Glutathione is critical for healthy immune and system function is necessary for proper processes

We chose P90 as the time of investigation, because this is a symptomatic stage with profound CSMN loss, and it coincides to the disease stage, when patients show symptoms and TDP-43 pathology begins to occur