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doi: 10.1016/0891-5849(94)90030-2

Study Design Type: Phase 3a, 68-week, multicenter, double-blind, placebo- and active-controlled trial Population: 3417 adults

Knockdown of the cGAS-STING pathway prevented astrocyte senescence both in vitro and in vivo , thereby ameliorating Parkinson's disease-like pathology in MPTP-treated mice, a model that exhibits persistent Parkinsonian symptoms

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