The inherent discrepancies in immune-metabolic baselines, gastrointestinal anatomy, and foundational gut microbiota compositionexacerbated by behaviors like murine coprophagiamean that preclinical mechanistic findings frequently fail to translate into consistent clinical efficacies
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J Biol Chem 277:2694426949 Couturier J, Przybyla-Toscano J, Roret T, Didierjean C, Rouhier N (2015) The roles of glutaredoxins ligating Fe-S clusters: sensing, transfer or repair functions
Ethics statement The animal study was approved by Lower Saxony State Office for Consumer Protection and Food Safety (LAVES, Oldenburg, Germany)