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Although regulating the MUFA/PUFA ratio by lactate through the SCD1/ASCL4 pathway does affect membrane lipid peroxidation sensitivity, this protective effect against ferroptosis may be more highly dependent on the state of the intracellular antioxidant system (83)

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Otsuka, M., Kato, N., Ichimura, T., Abe, S., Tanaka, Y., Taniguchi, H., Hoshida, Y., Moriyama, M., Wang, Y., Shao, R., Narayan, D., Muroyama, R., Kanai, F., Kawabe, T., Isobe, T., & Omata, M