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Upon subsequent re-exposure, the elicitation phase occurs, during which Langerhans cells present the allergen to the memory T cells, thus releasing inflammatory cytokines such as IFN-, TNF, interleukin 17 (IL-17), and interleukin 22 (IL-22), which may vary across the specific trigger [5, 9, 38]

Additionally, because BPC-157 products are unregulated, contamination with other substances represents a significant concern, and some studies suggest that between 12% and 58% of ergo-nutritional supplements may be contaminated with other substances

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The systemic nature of BPC-157 means it is effective regardless of the injection site, though proximity to the injury is often preferred in animal models