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The host liver can be preconditioned by small molecules to create amicable hepatic microenvironments, including endothelial disruption, microcirculatory dilation, instant blood-mediated inflammatory reaction (IBMIR) inhibition, and cell proliferation, which favor the engraftment and repopulation of the transplanted hepatocytes

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An application of cyclophosphamide (180 mg/kg i.p.) induced significant disturbances

doi: 10.20944/preprints201909.0043.v2 387 SweetmanEKleffmannTEdgarCde LangeMVallingsRTateW