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Additionally, glutamine metabolism in the mitochondrial tricarboxylic acid (TCA) cycle plays a key role in ferroptosis, and erastin-induced ferroptosis can be blocked by inhibiting glutamine decomposition or intracellular glutamine deficiency[44]

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Some women with PCOS have low levels of oestrogen and most women with hypothalamic amenorrhea have very low oestrogen

Resveratrol alleviates high glucose-induced oxidative stress and apoptosis in rat cardiac microvascular endothelial cell through AMPK/Sirt1 activation