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doi: 10.1371/journal.pone.0004871

The sugar sensing neurons of the gut, the way the vagus is wired, the fact that Omega 3, Omega 6 tend to improve the ratios tend to impact mood, with high omega 3, omega 6 ratios improving mood

Face serums and creams: Clinical standard: 1-3% concentration Maximum typically used: 4% concentration Application: Once or twice daily Duration: Minimum 8-12 weeks for visible results Eye area products: Concentration: 1-2% (lower for sensitive periorbital skin) Application: Once daily, typically evening Amount: Pea-sized for both eyes Scalp solutions for hair: Concentration: 0.5% solution common Application: 1-2ml to affected areas once or twice daily Duration: 3-6 months minimum for meaningful changes Higher concentrations do not always mean better results with topicals

em =450 nm) observed is proportional to the amount of GSSH available for conversion by GR, and to GXP4 activity