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In a cohort of pregnant women in Bangalore, India, with a high incidence of vitamin B-12 deficiency, we reported previously that women in the lowest tertile for plasma vitamin B-12 concentration during all 3 trimesters of pregnancy had significantly higher risk of IUGR that persisted after adjusting for maternal age, weight, education, and parity (12)

But, it can change based on how bad the deficiency is and what the patient needs

If so, older individuals with suboptimal dietary protein intake could be supplemented with Cys in order to cut down the potential pro-sarcopenic effect of APAP

Our laboratory has proposed a combinational drug therapy involving combined GSH supplementation and iron chelation for upcoming clinical trials for AD patients