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Paan, is a preparation that consists of betel leaf filled with areca nut, slaked lime paste, and other ingredients such as spices (cardamom and saffron), and sometimes sweeteners such as raisins, candied fruit

Statistical analysis Tobacco blends and smoke yields were statistically compared between different cigarette types by two-tailed, unpaired, Students t-tests or ANOVA analysis performed using Minitab v16 (Minitab Ltd, Coventry, UK)

The baseline study population of HNR consisted of 4814 participants

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